Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt.
Phytomedicine. 2014 May 15;21(6):871-6. doi: 10.1016/j.phymed.2014.02.002. Epub 2014 Mar 18. Diosgenin inhibits the migration of human breast cancer.
Abstract 2871: Diosgenin inhibits the proliferation of MCF-7 breast cancer cells through the demethylation of miR-145 gene. Fengqin Shi.
Abstract. 632. Constitutive over expression of Akt has been implicated in de novo resistance to current treatments in many cancer types.
Fatty acid synthase (FAS) expression is markedly elevated in HER2- overexpressing breast cancer cells. In this study, diosgenin.